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KMID : 0388419990080020059
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Konkuk Journal of Medical Sciences
1999 Volume.8 No. 2 p.59 ~ p.65
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The Effect of Clonorchiasis in Relation to the Serum Transaminase in the Region of South-Han River
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Kim Seog
Lee Jae-Dong
Lee Sung-Cheorl
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Abstract
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When we show mild elevation of the serum transaminase, clonorchis sinensis could be one of the etiologic factors for the alteration of hepatic function. The aims of current issue are to evaluate the positive rate of clonorchis cinensis in patients visited our hospital and the correlation between the infection rate of the clonorchis and the increased serum transaminase in patients who had eaten the raw freshwater fish in the Chung-Ju City. 85 patients who had eaten the raw freshwater fish and 2155 patients visited at Konkuk university hospital were examined by the stool examination. (1) The
percentage of the patients who showed the positive finding of clonorchis ovum on the stool test was 5.3% in whole patients. (2) The positive rate of the clonorchis ovum on the stool test was 17.6%, the rate of positive reaction of antibody in the serum was 12.9%, the sensitivity of the anti-CS antibody ELISA test was 66.7% and the sensitivity of the clonorchis ovum on stool examination was 55.3% in the patients who had eaten the raw freshwater fish. (3) The infection rate of the clonorchis was 27.1%, the positive rate of the ovum and the antibody was 3.5%, the positive rate of the antibody without ovum findings was 8.2% and the positive rate of the ovum without antibody findings was 5.9% in the patients who had eaten the raw freshwater fish. (4) There were a few experiences and no infection in the young people under 20, however the more infection rate was shown in the older people over 20. (5) The positive rate of ovum detection in the patients who showed the increased serum transaminase was 30.0% in the patients who had eaten the raw freshwater fish. (6) The positive rate of ovum detection in the patients who showed the normal serum transaminase was 22.9% in the patients who had eaten the raw freshwater fish. The percentage of the patients who showed the
positive finding of clonorchis ovum on the stool test was 5.3% in whole patients. Regarding to the patients who had eaten the raw freshwater fish, there was no significant correlation between the prevalence of C. sinensis and the findings of increased serum transaminase.
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KEYWORD
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clonorchiasis, raw freshwater fish, ova, C. sinensis antibody, transaminase
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